Tolibut

Tolibut
Clinical data
ATC code	None;
Identifiers
	IUPAC name 4-Amino-3-(4-methylphenyl)butanoic acid;
CAS Number	28311-38-8 ; 28311-37-7 (HCl);
PubChem CID	49344;
ChemSpider	44852;
UNII	UJ5N9SJ9NL;
CompTox Dashboard (EPA)	DTXSID00951003 ;
Chemical and physical data
Formula	C11H15NO2
Molar mass	193.246 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC=C(C=C1)C(CC(=O)O)CN;
	InChI InChI=1S/C11H15NO2/c1-8-2-4-9(5-3-8)10(7-12)6-11(13)14/h2-5,10H,6-7,12H2,1H3,(H,13,14); Key:MSZRPURXKHMSFF-UHFFFAOYSA-N;

Tolibut, also known as 3-(p-tolyl)-4-aminobutyric acid (or β-(4-methylphenyl)-GABA), is drug that was developed in Russia. It is an analogue of γ-aminobutyric acid (GABA) (that is, a GABA analogue) and is the 4-methyl analogue of phenibut, and is also an analogue of baclofen where the 4-chloro substitution has been replaced with a 4-methyl substitution. Tolibut has been described as possessing analgesic, tranquilizing, and neuroprotective properties. It is not fully clear as to whether the drug was ever approved or used medically in Russia.

Clinical data

ATC code	None
Identifiers
IUPAC name 4-Amino-3-(4-methylphenyl)butanoic acid
CAS Number	28311-38-8 28311-37-7 (HCl)
PubChem CID	49344
ChemSpider	44852
UNII	UJ5N9SJ9NL
CompTox Dashboard (EPA)	DTXSID00951003
Chemical and physical data
Formula	C₁₁H₁₅NO₂
Molar mass	193.246 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC1=CC=C(C=C1)C(CC(=O)O)CN
InChI InChI=1S/C11H15NO2/c1-8-2-4-9(5-3-8)10(7-12)6-11(13)14/h2-5,10H,6-7,12H2,1H3,(H,13,14) Key:MSZRPURXKHMSFF-UHFFFAOYSA-N

Tolibut

See also