Allylglycine
Names | |
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Preferred IUPAC name
2-Aminopent-4-enoic acid |
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.028.809 |
PubChem CID
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Properties | |
C5H9NO2 | |
Molar mass | 115.13 g/mol |
Appearance | white crystalline powder |
Density | 1.098 g/mL |
Melting point | 265 °C (509 °F; 538 K) |
Boiling point | 231 °C (448 °F; 504 K) |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Convulsant |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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147-195 mg/kg (mice, intraperitoneal) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Allylglycine is a glycine derivative. It is an inhibitor of glutamate decarboxylase. Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter. Allylglycine is known to induce seizures in animals studies, presumably due to this GDC-inhibiting activity.