AMY2B

AMY2B
Identifiers
Aliases	AMY2B, AMY2, AMY3, HXA, amylase, alpha 2B (pancreatic), amylase alpha 2B (pancreatic), amylase alpha 2B
External IDs	OMIM: 104660 MGI: 3714985 HomoloGene: 134663 GeneCards: AMY2B
Gene location (Human)
Chr.	Chromosome 1 (human)
End	103,579,534 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	113,231,368 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; right uterine tube; ; cerebellar hemisphere; ; gastric mucosa; ; left lobe of thyroid gland; ; tibial nerve; ; right lobe of thyroid gland; ; Achilles tendon; ; nucleus accumbens; ; gastrocnemius muscle;
	Top expressed in
	pancreas; ; islet of Langerhans; ; stomach; ; colon; ; esophagus; ; duodenum; ; jejunum; ; quadriceps femoris muscle; ; spermatid; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	catalytic activity; alpha-amylase activity; hydrolase activity; metal ion binding; hydrolase activity, acting on glycosyl bonds; cation binding;
Cellular component	extracellular region; extracellular exosome;
Biological process	digestion; metabolism; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	280
	100043686
	ENSG00000240038
	ENSMUSG00000093931
	P19961
	P00688
	NM_020978; NM_001386109; NM_001387437
	NM_001160151
	NP_066188
	NP_001036176; NP_001153622; NP_001153623; NP_001153624
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-amylase 2B is an enzyme that in humans is encoded by the AMY2B gene.

Function

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside] bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.